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Clinical Question: Is hypertension is a risk factor for
hysterectomy?
Bottom Line: Hypertension seems to be a risk factor for
hysterectomy performed for benign diagnoses, and thus contributes to women
undergoing hysterectomy having an increased risk of cardiovascular diseases.
It might be relevant to pay increased attention to the blood pressure in
candidates for hysterectomy, as optimal antihypertensive treatment could
decrease their otherwise increased risk of cardiovascular disease years
after hysterectomy.
Reference: Hypertension is associated with an increased risk for
hysterectomy A Danish cohort study. Eur J Obstet Gynecol Reprod Biol. 2005
Oct 1;122(2):218-224.Settnes A, Andreasen AH, Jorgensen T.
Study Design: Cohort Study
Synopsis: To assess whether hypertension is a risk factor
for hysterectomy, endometrial resection, and myomectomy.Self-report
questionnaires were collected from 81% of 1959 Danish women aged 30 or 40
years selected at random in 1976-1991, in four different cohort studies.
Baseline data included standardized information about cardiovascular
diseases, hypertension, use of medicine, gynecologic history, social
background, and life style factors. Weight, height and blood pressure were
measured. The women were followed via central registers to assess the
incidence of hysterectomy, endometrial resection, and myomectomy performed
for benign diagnoses. Cox regression analyses were used to control for
confounding. The average time to follow-up was 15 years, and 135 operations
performed for benign diagnoses were identified. Women with a history of
hypertension had a double risk of having an operation compared to women
without hypertension, independent of confounders.
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